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Levine I et al

Otterbein LEBFH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

and 2) supplying glutamine for glutamate and GABA synthesis in the glutamine-glutamate-GABA cycle, regulating the excitatory and inhibitory synaptic transmission of neurons ( Urea cycle-ammonia detoxifying effect accounts for only 35%

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The anti-apoptotic effects of GLP-1 have been found in animal models and in cultured pancreatic beta cell lines 6,7